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GP participated study coordination.
MC participated study design, genetic analysis and drafting the manuscript.
Both authors have participated study discussion and manuscript preparation.
DGC participated study design, data interpretation, and manuscript preparation.
JZ and XY participated study design and drafted the manuscript.
AL participated study design, data collection, statistical analysis, data interpretation, manuscript preparation, MKG participated study design, data collection, statistical analysis, manuscript preparation, literature search.
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The study was approved by the local ethics committees at all participating study centers.
All participating study sites received approval from their respective local institutional review board.
The dataset supporting the conclusions in this article is owned by the participating study centres.
They let people participate, study and train in inaccessible or impossible areas.
The authors are also indebted to participating study volunteers.
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