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theological scholar and advocate of the English reform movement within the Roman Church who later recanted his unorthodox views and participated in the repression of other reformers.
Furthermore, the inhibition of BTF3 participated in the repression of transcription and protein synthesis in apoptotic K562 cells [ 27], while change in BTF3 expression is linked with apoptosis in BL60 Burkitt lymphoma cells [ 28].
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E2F6 lacks the sequences necessary for either pocket protein binding or transcriptional activation and it participates in the repression of E2F-responsive genes through recruitment of a mammalian polycomb complex.
At face value, therefore, our data support the idea that multiple PRC1 components participate in the repression of INK4a in human fibroblasts.
Recent studies have demonstrated that Polycomb group (PcG) proteins participate in the repression of developmental genes that are activated during ESC differentiation [10], [39], [40].
Polycomb proteins are repressors of nucleoplasmic gene transcription (Bannister and Kouzarides 2011), and perhaps they also participate in the repression of Pol I transcription.
These findings suggest that PnTGS1-like may participate in the repression of AES formation in nucellar cells surrounding the legitimate germ cell lineage.
Because Brachyury, Slug and Snail all participate in the repression of E-cadherin expression, it appears that multiple pathways can lead to EMT.
Indeed, Kdm6a/Utx has been shown to be necessary for somatic cell reprogramming towards pluripotency [ 40], which is accompanied by a reactivation of the inactive X, and H3K27me3 demethylase activities participate in the repression of Xist in ES cells [ 41].
This implies that miRNAs developmentally down-regulated at earlier stages participate in the repression of a number of key neuronal genes at the time when neuronal network activity is undetectable [ 4, 20].
Baf250a and Baf250b, for instance, are mutually exclusive, and the corresponding Baf250a- and Baf250b-associated complexes have antagonistic effects on cell cycle progression, with Baf250a participating in the repression and Baf250b in the induction of key cell cycle regulators [71].
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