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They participate in the genesis of corneal stroma during the 5th week of embryonic development.
It is generally believed that neurotransmitters, including acetylcholine (ACh), participate in the genesis of afferent neural output from the carotid body and modulate the function of chemoreceptor cells (glomus cells).
Supporting the hypothesis that NO might also participate in the genesis of pain, nitroglycerin, by provoking vasodilatation via NO formation, is able to induce in healthy subjects an immediate, short-lasting, bilateral fronto-temporal and pulsating headache, that can be aggravated by routine physical activity [71].
Early-onset, autosomal dominant, familial Alzheimer's disease (AD) is caused by mutations in proteins that participate in the genesis of amyloid peptides.
In addition to its implications in macrovascular disease, fibrinogen may also participate in the genesis of microvascular complications in DM.
Both hypoxemia and sleep deprivation are frequently present in human patients with OSAS, and therefore may participate in the genesis of an inflammatory response [ 13].
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Thus, we speculate that volume overload participates in the genesis of increased pulmonary arterial pressure in hemodialysis patients.
It remains to be clarified whether leptomeningeal pathology participates in the genesis of PMG or represents a secondary change.
The generalized systemic immune activation that follows bloodstream invasion participates in the genesis of widespread endothelial injury and diffuse tissue damage, culminating in lethal septic shock [ 30, 31, 32].
The fact that c-Src and HER1 are co-overexpressed in many of the same tumor types suggests that these two kinases may participate in regulating the genesis and/or progression of human cancers.
Although the protective role of the macrophage is dominant, this cell may participate, directly or indirectly, in the genesis of two major groups of chronic pulmonary disease, interstitial fibrosis and emphysema.
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