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Advances in single-cell RNA-sequencing technology are making it possible to identify the many different types of cell that participate in the assembly of brain structures.
Our studies suggest that the AA' loop in IL-3 and the analogous region in GM-CSF participate in the assembly of the dodecamer.
A similar domain gp27 is known to participate in the assembly of the needle apparatus in T4 tail spike protein [9].
These snoRNAs associate with pre-rRNA as snoRNP complexes and participate in the assembly of ribosomal subunits [ 30].
We propose a model in which δ-tubulin and other components participate in the assembly of the basal body.
In general, the cytoplasmic domains participate in the assembly of juxtamembrane complexes that regulate cell signaling and the organizational state of the actin cytoskeleton.
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We designed alternative P14 (L5c-L2) interacting modules participating in the assembly of P5 and ΔP5 and investigated their ability in the context of complex formation of the two-piece ribozyme and in vivo splicing of the unimolecular intron ribozyme.
To understand how cells regulate the transformation of lamellipodia into filopodia, and to determine the major factors that control their transition, we studied actin self-assembly in the presence of Arp2/3 complex, WASp-VCA and fascin, the major proteins participating in the assembly of lamellipodia and filopodia.
To this end, in the present work we study a system containing the major proteins participating in the assembly of lamellipodia and filopodia: a) the constitutively active VCA [26] (or WA [8]) domain of WASp; b) Arp2/3 complex; c) fascin, and d) actin monomers.
BE, JLW, BAJ participated in the assembly of the database.
OD participated in the assembly of the data, and participated in drafting the manuscript.
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