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Secondly, we used a pragmatic approach, pooling participants with comparable migration motives and patterns (i.e. Italian, Spanish and Portuguese subjects).
We also found the occasional Merkel cells in both patients with carpal tunnel syndrome and control participants with comparable morphology (Fig. 3B).
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By comparing the intervention participants with a comparable control group we examined the impact of intervention on medication use, and other health care service utilization.
The propensity score matching yielded two well balanced treatment groups and removed potentially influential participants with no comparable controls.
Brightly stained myelinated fibres were present in some of these dermal nerve bundles in both patients with carpal tunnel syndrome (Fig. 3C) and control participants with a comparable percentage of PGP+ dermal bundles containing MBP+ fibres [median (IQR) carpal tunnel syndrome: 1.22 (0.38); controls: 1.31 (0.35), P = 0.38, Fig. 3E].
Base-line findings confirm that randomisation of participants was successful, with comparable characteristics between intervention and control groups.
The analysis compares participants on the programme with "comparable" (as determined by sophisticated statistical techniques) non-participants.
Participants with diabetes were comparable with those without diabetes for most characteristics except BMI.
Apart from younger age and HbA1c levels, participants with diabetes were comparable to the control group.
To ensure that participants could perform grinding with comparable muscle strength between sessions, another group of six participants who reported increased discomfort while grinding with strips compared with grinding without strips performed the same experimental tasks while EMG was recorded from the masseter (WEB-1000; Nihon Koden, Tokyo, Japan) on the grinding side without fNIRS recording.
The effect size estimates were based on single studies on physical exercise and CBT with comparable participants and methods, as well as comparable or equivalent primary outcome measures (Broocks et al., 1998; Clark et al., 1994; Clark et al., 1999).
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