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The covering letters kept the study participants updated and always included details of how to contact the research team.
Participants updated medical history annually (OS) or semiannually (CT) through a mailed self-administered or telephone-administered questionnaire.
(P6) Most participants updated the health diary on a daily basis, while a few updated it for several days at once.
For long-term studies, the importance of participant involvement, keeping participants updated and reliable routines for feeding back clinically relevant results obtained through genetic tests has been stressed [ 4, 8].
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Follow-up questionnaires are sent biennially to participants, updating information on other risk factors and newly diagnosed diseases.
Thus, selective updating, whereby participants update their beliefs when receiving desirable information relative to undesirable information, was enhanced by L-DOPA.
As part of the home visit at age 53 years, trained research nurses measured height and weight and took a non-fasting venous blood sample according to standardized protocols [ 13], and interviewed participants, updating previously collected information on smoking habits, live births, doctor-diagnosed diabetes, and current or most recent occupation.
Each participant updates the declaration of interests at the opening of the meeting.
All records were retrieved and the follow-up of surviving participants was updated until 2006.
Vital status for cohort participants was updated through 31 December 2011.
The dates of death of HUNT participants were updated regularly from the National Registry.
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