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These proteins might be either entirely disordered or partially disordered, characterised by regions spanning just a few (<10) consecutive disordered residues (loops in otherwise well-structured proteins) or long stretches (≥30) of contiguously disordered residues.
Thus, proteins might be either entirely disordered or partially disordered, characterised by regions spanning just a few (<10) consecutive disordered residues (loops in otherwise well-structured proteins) or long stretches (>30) of contiguously disordered residues.
Such cooperative folding was observed experimentally for smaller partially disordered multi-domain proteins18.
"They tend to migrate to the point where they are partially ordered, partially disordered," he said.
Upon binding of the fourth inhibitor the dimer interface, however, becomes partially disordered.
Here we show, via high-resolution transmission electron microscopy, that the structural dimorphism is accommodated in the form of partially disordered nanoscale stripes.
While the outer membranous regions are partially disordered, the TM region is clearly visible in the electron density map, including the covalently attached all-trans retinal (Supplementary Figure 3).
The (partially) disordered local moment picture and Monte Carlo simulation method were combined to study the magnetically disordering effects on the thermodynamic properties in Fe Cu alloys.
These results confirmed that the mesophase was composed of partially disordered alkyl chains anchored to unperturbed metal basal plane aggregates.
The aggregated phase started with the emergence of stable, but partially disordered decamers.
Even though the αC-helix is partially disordered in the crystal structure, the groove is clearly defined.
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