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The influence of nitrogen concentration on the local mechanical properties has been studied by repeating these indentation matrices in the same area after successive partial removals of the nitrided layer.
Our findings indicate that protein-protein binding sites are generally protected from alternative splicing-mediated partial removals.
As shown in Figure 1B, also in this case partial removals of the interface are significantly prevented, though the significance is lost at a lower threshold compared to heterodimers.
Both for heterodimeric and homodimeric interfaces, the results of the two tests showed again a significant protection from partial removals, and this was true irrespective of the threshold values (these results are shown in the Additional file 3).
These results suggest that alternative splicing tends to avoid partial removals of heterodimeric interaction sites, while being quite indifferent to large excisions - possibly because they occur along with major rearrangements of the protein, in which cases there might be no pressure in maintaining the interaction.
The test showed a significant protection form partial removals both for heterodimeric and homodimeric interfaces, even if homodimeric interfaces appear to tolerate larger removals compared to heterodimeric ones (again, the frequency at which they undergo large removals is higher than that of the background, but not in a statistically significant way).
Similar(53)
The most common procedures fall within the "cut, some flesh removed" category, and involve complete or partial removal of the clitoral glans.
Daily treatment with cortisol is essential if the adrenal glands have been completely removed and may also be necessary after partial removal of these glands.
No CPs were removed at 10-20 bar (Figure 4b, c), and partial removal was observed at 30 bar (Figure 4d).
The girls suffered either type one or type four FGM with a cut or partial removal of their clitoreses which did not leave scar.
The data was culled from patients who underwent 12 complex surgeries from five disciplines, such as total hip replacements and partial removal of the oesophagus.
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CEO of Professional Science Editing for Scientists @ prosciediting.com