However, PAB3 does correct the temporal lag prior to the entry of mRNA into the decay pathway in pab1 mutant yeast, but only partially, suggesting only partial function in mRNA decay [ 38].
The 344P (Arg→Pro) mutation is functionally dead, whilst 337C (Arg→Cys) retains partial function and along with wild-type p53 these two mutants were used as controls in the various assays.
The majority of RTT patients carry missense and nonsense mutations in the MECP2 gene leading to a hypomorphic protein with partial function, while null mutations leading to the complete absence of a functional protein are relatively rare (21, 40, 41).
The functional assay in vivo was taken as an indication for partial function.
However, your interpreter must support partial function applications.
In contrast, mutation of the Mcp dCTCF site does not affect Pita binding, and this mutant boundary retains partial function.
β1 can provide partial function for axoneme assembly but cannot make the central microtubules [14].
This result is of special interest since 'partial correctness' has already been formulated in predicate calculus and in partial function logic for many classes of algorithms.
A partial function is a one-variable function obtained from a function of several variables by assigning constant values to all but one of the independent variables.
Fortunately, more than 90% of patients with FKRP mutations contain at least one allele of the L276I mutation, which retain at least partial function as demonstrated in patient muscles and in the mutant mouse models.
Within a community, the system is implemented in a graduated manner based on available resources, and is designed to not rely on the whole system being implemented first to provide partial function.
