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The conservative mutation of Gln121 to asparagine resulted in partial decreases in efficiency of both uptake and binding (Fig 3, Supplementary Table S1 and Supplementary Fig S4), while its replacement with leucine, as is observed in the uridine transporter Fui1 (de Koning & Diallinas, 2000; Weyand et al, 2008), reduced uptake and binding yet further.
Partial decreases in hypoxia-induced lipid droplets were observed for glial knockdowns of the Drosophila orthologs of genes encoding enzymes converting fatty acids into lysophosphatidic acids (GPAT, CG3209, one of three glycerol-3-phosphate acyltransferases) or lysophosphatidic acids into phosphatidic acids (AGPAT, CG4753, one of four 1-acyl-sn-glycerol-3-phosphate acyltransferases).
The other two dogs showed only partial decreases in serum potassium concentrations (from 5.3 and 4.4 mmol L−1 to 4.6 and 3.8 mmol L−1, respectively), and QTcV did not fully increase to baseline values (from 221 and 207 ms to 255 and 253 ms; slopes: −7.53 and −8.07 and R: 0.97 and 0.93, respectively).
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COX10 depletion also resulted in a partial decrease of the respiratory rate (about 30%) which was partially compensated by AOX expression (Fig 2B).
Both supports were always present during the study and a partial decrease in size and weight was detected only with control sponges, both seeded and unseeded.
Replacement of amino acids in other positions (Tyr-5, Leu-7 and Pro-9) gave partial decrease of efficacy, respectively, five, six and six out of seven piglets were immunocastrated.
When the drill bit crosses a permeable fracture zone, the well records a partial decrease in the outflow or even a total loss of mud circulation.
It also evidences that single reduction at 800 °C does not violate the integrity of the zirconia skeleton and a partial decrease in strength is caused by nickel phase transformation.
Our data are consistent with this finding as inactivation of emm1 led to a partial decrease in biofilm formation.
In the D159A mutant, only a partial decrease (20%) in activity was observed for 5' phosphatase activity suggesting that this reaction could also be metal ion dependent.
The insertion causes a partial decrease in the Aif protein to about 20% of the amount seen in wild-type mice.
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