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By presenting compositional information from the entire painted surface in a visual manner, the element distribution images could comprehend a large part of methods and materials used by De Heem, reveal changes in the painting process, visualize the condition of the art works and conservation treatments, and gain profound insights into how the paintings were constructed.
This paper constitutes the first part of methods development for a case-control study summarily described in the Methods/Design section.
AP designed the study, acted as a demonstrator to carry out the 'dental part' of methods, involved in revising the manuscript critically, PA supervised the whole progress of study, AP contributed in data analysis and manuscript editing.
According to Methodological quality assessment (the 4th part of Methods section), HE4 tests with CMIA, CA125 tests with EIA and RIA were regarded as high Concern Regarding Applicability.
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This study yields useful information, being a fundamental part of method validation.
OPNA-exposed quality control plasma samples were characterized as part of method validation.
This PQ tests could be considered part of method validation, which will be the subject of a dedicated guideline.
They also should be able to interpret many statistical tests, as an integral part of method comparison and assay validation.
IYK collected the clinical data and wrote the clinical part of method.
System suitability is an integral part of method development program and is performed prior to every analysis to ensure the suitability of the system on which validation is to be carried out.
This study was part of a methods course in a 4-year university in the USA.
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