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Alpha enolase is a cytoplasmic glycolytic enzyme (Chang et al, 2003) and is downregulated in non-small-cell lung carcinoma, and so the upregulation of this protein with Gefitinib could play a part in the reversal of tumorigenesis.
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This interesting drug interaction can be explained in part by the reversal of the "double lock" epigenetic mechanism for gene silencing by DNA and histone methylation.
However, we observed that metformin-treated cells maintain their mitochondrial membrane potential in part due to the reversal of the ATP synthase thus allowing accumulation of metformin in the mitochondrial matrix.
In May, King expressed skepticism about the decision to grant asylum to Onyango, alleging that "favoritism or judicial bias" may have played a part in the eventual reversal of a previous ruling against her.
He insists that external pressure played no part in the reversal, that it was simply the normal review procedure taking effect after a poor initial assessment of risk.
In some parts of the world, the reversal of fortunes has been stark, notably in Asia.
We conclude therefore that eye movement patterns play a significant role in shaping observers' experience with the stimulus, possibly playing a part in the formation of reversal location distributions.
The main part of the paper covers the reversal of structured control flow graphs.
After Gordon Brown took over as prime minister, the attorney general, Lady Scotland, was given no part in the decision, a reversal of the position adopted by her predecessor, Lord Goldsmith, who claimed he had a duty to be party to it.
She said the reversal of Planned Parenthood funding played no part in Teer's departure, describing it as "a natural progression in her career".
Part of this is because the viral genome expression is impacted by host chromatin dynamics, including in HIV LTR transcription initiation and the reversal of viral latency.
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