Taken together, the substrates mainly bind to the subsites − 1 to − 3 with the highest affinity, while the part bound to the reducing end would be hydrolyzed.
As described earlier [ 28], dihydroxylated TIQ derivatives are in part bound to sulfo- or gluco-residues which can be deconjugated by incubation with arylsulfatases and β-glucuronidases.
Enzyme treatment (pronase), inhibition or simultaneous labelling of surface Ig and Fc receptors showed that the characteristic surface Ig found to AML cells is, at least in part, bound to Fc receptors.
I prefer to think of him as our supreme actor-poet-playwright, reliving recent history because it's such a rattling good yarn, packed with great parts, bound to break all box-office records.
The graphene film is separated from the bulk by a carbon-rich interface layer (hereafter called the buffer layer) which in part covalently binds to the substrate.
In other words, the specificity of an antibody relies on the uniqueness of the protein part it binds to (i.e. the epitope).
Notch is a major oncogenic driver in T cell acute lymphoblastic leukemia (T-ALL), in part because it binds to an enhancer that increases expression of MYC.
Because TFIID has many moving parts as it binds to DNA and gets ready to transcribe a gene, averaging all the frozen positions produces a blurred image.
We speculate that oncogene expression is driven in Daxx-deficient MEFs in part because Pten still binds to H3.3 in the absence of Daxx expression (Supplementary Fig. 8h).
Those taking part are bound to be attacked by Mr Mugabe's "war veterans", who have already banned independent newspapers in many rural areas, and have beaten, and sometimes killed, opposition supporters.
