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Neither ghrelin nor leptin levels varied by parity category after adjustment for age and diabetes.
Age-adjusted ghrelin and leptin levels did not differ by parity category.
Multivariable logistic regression was performed to identify covariates associated with type 2 diabetes and to compare the odds of type 2 diabetes by parity category, using the low parity category as the referent group.
The highest risk of any parity category is observed among the parity 8-9 categoRR (RR = 9.98; 95% CI 6.95, 12.05).
In the material used in the current study, peak milk yield was virtually equal across calving to conception intervals within each parity category (Table 2), and therefore this bias of performance is believed to be minimal.
The prevalence of hypertension and type 2 diabetes increased significantly by parity category; diabetes prevalence was 25% in the low parity group, 30.3% in the medium parity group, and 50% among women with ≥6 births (P = 0.048).
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None of the parity categories reached a p level of <0.05.
The variables included in the final adjusted model were maternal age (10-year categories) and parity (categories).
Additional considerations include the small sample sizes when stratified into parity categories, as reflected by the wide CIs in multivariable regression analysis.
The numbers of observed cases of CC and CIN3 and person-years at risk were counted by 5-year age groups and separately for four parity categories (5, 6, 7 and 8+ children), four categories by the age at first birth (<20, 20 24, 25 29 and 30+ years) and three birth interval categories according to the average interval between the first five deliveries (<2.0, 2.0 3.0 and >3.0 years).
Independent variables included: maternal age (three categories), parity (four categories), ethnicity (five categories), education (five categories), household income (five categories), relationship status (living with a partner versus not), and pregnancy intention (planned versus unplanned).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com