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The parental virus (virion) gives rise to numerous progeny, usually genetically and structurally identical to the parent virus.
The first step in the cycle of infection is that the invading parental virus (virion) must attach to the surface of the host cell (adsorption).
The rescued virus was indistinguishable from its parental virus.
The tagged viruses were genetically stable and exhibited similar growth properties with their parental virus.
None of these alterations changed the growth phenotype of the parental virus.
Recombinant influenza virus immune mice showed better cross protection than parental virus immune mice.
Pigs intramuscularly immunized with the recombinant virus produced a similar humoral response to that elicited using parental virus.
Pigs were experimentally infected with the parental virus or the recombinant virus recovered from pSVL-f02 transfected cells.
By various virological assays, our results indicated that the rescued virus exhibited similar biological properties with the parental virus.
However, Gmem rRSV-infected mice developed good antibody responses and were fully protected against subsequent intranasal challenge with parental virus.
It is considered as unlikely that the JE live vaccine SA14-14-2 reverts itso its parental virus virulence by random amino acids mutations.
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