Sentence examples for parent molecules are from inspiring English sources
Results from the in vitro evaluation of AC163794 and parent molecules are summarized in Table 1.
The parent molecules were decorated with linkers of different length, carrying an amino group to catch a putative anionic function outside the recognition site of the receptor.
Quantum chemical similarities of parent molecules were extended using the corresponding matrixes after substitutions of halogen atoms for hydrogen and nitrogen for carbon giving matrixes capturing the influence of halogens (three kind of matrixes for halogens Hal = F, Cl, and I) and N (for both N = Nring, NFunctional. Group) on the electronic structure of each molecule.
The formation pathways of H3+ via the roaming H2 mechanism for methanol and ethanol, which are triggered by the strong-field double ionization of the corresponding parent molecule, are shown in Fig. 1.
The integrated atomic properties for the hydrogen atoms of the X-H...Y H-bond and the difference of the properties between the complexes and parent molecule are collected in Table 6.
Structural models of mutants generated using the SwissPdb Viewer using BSX (PDB id-2FGL) as a parent molecule are shown in Figures 1D J.
A supplementary experiment on decane indicates that the formation via single step rearrangement of the parent molecule is not likely.
The results might imply that the π-conjugation system of C60 parent molecule is isolated into smaller separated parts.
Intriguingly, the most active compound with ten-fold higher activity than the parent molecule was realized by sheer serendipity to employ a silica gel based rearrangement that was further explored using nuclear magnetic resonance spectroscopy and density functional theory calculations.
The varying biological activity of these analogs and bulk of substituent at position-7 of the benzofuranone ring system of the parent molecule was rationalized utilizing predictive in silico molecular modeling.
The rates of conversion into the parent molecule were determined by incubating the prodrugs in fresh rabbit or human tears or in a phosphate buffer solution (PBS) at pH 7.4.
