Sentence examples for paramount functions from inspiring English sources

In a cell nucleus, chromosomes are folded in a highly specific manner, which connects strongly to some of their paramount functions, such as DNA replication and gene transcription.

However, in spite of these paramount functions that may be altered during knee degeneration, the role of menisci in the onset and development of OA is not well understood.

What a wake-up call for those of us who had assumed that the engaging Adam Boulton's paramount function as a television presence was to warn Clive Anderson what he'll look like if he puts on seven stone.

The paramount function of the website is its utility as a diagnostic aid.

This interplay is supported by an earlier study, which revealed that adenylate cyclase is activated by light, but phosphodiesterase is not (Kolarova et al., 1992) – which in view of the presented data could due to a paramount function, i.e. negative action of ENVOY.

This process is associated with dramatic transcriptome changes, pointing to a paramount role for transcription factors in DC activation and function.

Furthermore, it is believed to have a paramount role in antitumor immunity at the site of inflammation owing to its neutrophil-mobilizing functions.

Since KSHV LANA plays a major role in both maintenance of viral latency by tethering the viral episome to host chromatin and tumor induction by interacting with nuclear proteins to subvert normal host cell function, its transport to the nucleus is paramount for its function.

Mr O'Brien may justifiably claim a right to reputation, but the right of the press to report parliamentary proceedings is paramount in a functioning democracy," Reidy said.

It is therefore paramount for the function of RND transporters that an effective signaling pathway is established between the two domains.

This contractile capability is paramount to proper function of this blood vessel layer.