In establishing the nation's first continuously operating university press at The Johns Hopkins University in 1878, the University's presIdent, Daniel Colt Gilman, described the three paramount functions of a university as teaching, research, and the dissemination of the results of scholarly inquiry, not only in the classroom but beyond its walls.
This interplay is supported by an earlier study, which revealed that adenylate cyclase is activated by light, but phosphodiesterase is not (Kolarova et al., 1992) – which in view of the presented data could due to a paramount function, i.e. negative action of ENVOY.
However, in spite of these paramount functions that may be altered during knee degeneration, the role of menisci in the onset and development of OA is not well understood.
In a cell nucleus, chromosomes are folded in a highly specific manner, which connects strongly to some of their paramount functions, such as DNA replication and gene transcription.
It is therefore paramount for the function of RND transporters that an effective signaling pathway is established between the two domains.
This contractile capability is paramount to proper function of this blood vessel layer.
In platelets ILK associates with β1- and β3-containing integrins, which are of paramount importance for the function of platelets.
This study indicates that cell-cell adherent junction is one of the paramount factors required for the function of insulin-secreting β-cell.
The patency of pancreaticojejunostomy anastomosis is of paramount importance in conserving the exocrine function of the pancreas in patients who have undergone partial pancreatectomy.
An appropriate balance between MMPs and TIMPs is considered to be of paramount importance to preserve normal structure and function of the vessels.
