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I have learned that the paramount fact of American Democracy today is that there have been absolutely no great presidents since FDR (democrat) and Ike (republican).
The paramount fact is that entire republican party is dedicated to continuing the destruction of social security, medicare, education, health, economic stability, American industry and jobs and The American Way of Life.
The paramount fact is that there is no national and international progress required to save the environment, to meet the long-term needs of future generations, because there are no national and international leaders making it happen!
Most unfortunately TPR, it looks like your side will keep getting your way because the paramount fact is that neither democratic politicians nor university academicians are implementing solutions to prevent global warming disaster.
We must all focus first and foremost on the paramount fact that We have so much to lose and so little time to save what is left of our quality of life.
The paramount fact is that our Homo sapiens brain simply has not evolved far enough beyond the Pan troglodytes brain to allow us make long-term plans and actions to prevent far-off catastrophes engineered by our own species.
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Comment is paramount; facts are relegated.
A paramount historical fact is that it was COOPERATION that made it possible for our Founders to create the United States and our Constitution in the first place.
She discusses not only the awesome size of the thing, but the problems with antibiotic resistance and (probably of paramount importance) the fact that it's not illegal to sell food with salmonella, even though a policy like that could be enacted.
But the transition issue I think that's paramount is the fact that the contract and the management of the contract that we criticize in this -- most recent audits, the DynCorp contract, is up for bid right now in Iraq, and no surprise.
Owing to the crucial function of miRNAs in controlling mRNA expression, the discovery of currently unknown targets of specific miRNAs is paramount, but the fact that most miRNAs are only partially complementary to their target genes hinders this identification.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com