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The affecting parameters were analyzed by using central composite design method.
Associations between methylation of SFRP3 and clinical parameters were analyzed by using a chi-square test and Fisher's exact test, where necessary.
The mean echocardiographic measurements over three consecutive respiratory cycles were recorded, and parameters were analyzed by using frozen images from M-mode recordings.
All these laboratory parameters were analyzed by using commercially available Randox reagent kits and with help of a fully automated biochemical analyzer (Model-Fully, Biochemical System International, Italy).
To test dose proportionality, the primary pharmacokinetic parameters were analyzed by using a regression model on the log-transformed pharmacokinetic parameters (AUClast and/or AUC0 ∞ and Cmax) versus log-transformed dose, and dose proportionality was assessed with a lack-of-fit test.
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The thermodynamic parameters are analyzed by using the enthalpy method.
Then, the relationship between the aging conditions and the corresponding PSV parameters was analyzed by using the statistical technique analysis of variance (ANOVA).
The effects of different laser parameters are analyzed by using a combination of advanced sample preparation and ultra-high resolution scanning electron microscopy on a nanoscale level and a specific combination of mechanical tests on the macroscopic level.
The comparison of categorical parameters was analyzed by using Chi-Square test or Fisher's exact test.
The correlation between the parameters was analyzed by using the Pearson's test when the distribution was normal and by Spearman's rank test in the case of not normal distribution.
Qualitative parameters were analyzed by use of a 2 × 2 contingency table and Chi test or Fisher's exact test as appropriate.
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