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The genes are the parameters to be optimised and the organisms are solutions to the optimisation problems.
The suggested MILP formulation allows structural and operational parameters to be optimised simultaneously and the procedure is robust enough to tackle real industry problems.
In the planning stage of a chimney the diameter of the chimney, the height of the chimney, the size of the allowed heat loss etc. are typical parameters to be optimised.
The principal idea behind DE is to represent the parameters to be optimised as vectors where each vector is a population member whose fitness is described by the cost function value.
The temperature, the extraction time and power, the solvent volume, and the concentration of different solvent mixtures are the most common parameters to be optimised.
[It is also possible to optimize the selection proportions by adding them to the list of parameters to be optimised, effectively giving an optimised multistage selection scheme].
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The pitch angle (theta) is introduced as an additional parameter to be optimised.
Since two parameters needed to be optimised for this model, the length of each optimisation phase in the WAAC algorithm was extended to 150 iterations and the algorithm was run for 1500 iterations in total.
This will only be computationally feasible where the model has a small number of parameters which need to be optimised and where the parameter optimisation can be efficiently carried out.
Moreover, the set-up and the process parameters that need to be optimised for the removal of silicon impurities are complex and hazardous and result in a significant increase in the cost of production34.
An additional difficulty in the development of QSAR models is the fact that some regression methods have parameters that need to be optimised to obtain the best performance for a particular problem.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com