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The FoSTeS [ 141] and MMBIR [ 142] models propose that the lagging strand from one replication fork can disengage and invade another fork that is probably close to it in 3-D space based on microhomology and continue replication there, leading to deletions, duplications, inversions and/or translocations based on the parameters of the situation.
Notably, duplications, deletions, inversions and translocations of whole genes would not have been possible without a mechanism to enact them, and there is elegance in the mechanism of homology and recombination that is able to produce quite different outcomes based on different parameters of the situation, and that indeed is also the basis of sexual recombination.
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Accordingly, the mean arterial blood pressure, heart rate and the calculated pressure-rate product were taken as parameters of the hemodynamic situation.
A modified Reynolds number is developed based on an equivalent diameter including characteristic parameters of the flow situations under consideration.
Parameterized states-of-affairs can be restricted by other parameterized state-of-affairs, as in (10), where the subject role for the property of taking a shower is restricted to individuals who are singing: Properties and relations can be produced from parameterized states-of-affairs by absorbing parameters: Parameter absorption is the situation theory analogue of λ-abstraction.
We find that recall concern, propensity to reduce consumption beyond the recall parameters in the situation of both specific branded and unbranded products, and media reliance hold strong, direct effects on broad consumption changes.
The calculated results are not in good agreement with the data in the cases of four and seven estimated parameters, whereas the situation is improved in the case of three estimated parameters.
The limitation here is the need to find starting values for the parameters which are representative of the situation under consideration.
The challenge here is the need to find starting values for the parameters which are representative of the situation under consideration and to ensure that the solver used is stable with respect to measurement noise and limited data.
It therefore follows that any changes in the trend of these parameters could reverse the situation and increase the effects of temperature extremes on mortality.
The parameters of their particular situation, Ms. Shepley explained, were clear from the start.
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