It is very likely that ZNF143 might not only regulate basic cellular functions at the transcriptional level, but be the parameter of cell proliferative activity, very similar to the widely accepted Ki67 (MIB-1) protein (Burger et al, 1986; Oka et al, 2011), and subsequently be promising targets for lung cancer diagnoses and therapies.
Cultured and primary β-cells differ in important parameters like proliferative activity.
We also aimed to evaluate the association between the extent and intensity of expression of HSP staining and various clinicopathological parameters, tumor proliferative capacity, and patients' survival.
The present study is designed to determine the effects of neonatal and prepubertal exposure to BBP on rat mammary gland at different stages of development using morphological parameters of gland differentiation [ 13, 14], proliferative index and the genomic expression profile.
Then, we have used morphological parameters of gland differentiation [ 16, 17], proliferative index, and genomic signature as biomarkers for detecting how prenatal exposure affects the post-natal development of the mammary gland.
In view of the previous considerations, the present study aimed to assess immunohistochemically RCAS1 expression in 54 gastric adenocarcinoma specimens and to evaluate the association of RCAS1 expression levels with clinicopathological parameters, tumor proliferative capacity, and patients' survival.
For this purpose, we evaluated clinical-pathological parameters and proliferative and apoptotic activities in a series of 130 symptomatic and 161 screen-detected tumors.
Proliferative retinopathy usually requires treatment with laser photocoagulation akin to the treatment of proliferative diabetic retinopathy [6].
To profile vitreous cytokine expression of proliferative vitreoretinopathy (PVR) patients.
However, the use of proliferative undifferentiated pluripotent cells carries the risk of teratoma formation.
The source of proliferative cells varies among the organisms exhibiting epimorphic regeneration.
