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The NURBS parameters of expression model were optimized by an improved Genetic Algorithm (GA).
When a significant relationship between survival and parameters of expression in qRT-PCR existed, we identified an optimal cut-off by using the maximization of the hazard ratio.
Two parameters of expression that are predicted to be important for SHH morphogen function, i.e. levels and temporal extent of exposure (Yang et al., 1997; Ahn and Joyner, 2004; Harfe et al., 2004), were both affected by the deletion.
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Two parameters, induction of expression and standard deviation among untreated samples, identified 378 candidate methylated genes, many relevant to TGF-beta signaling.
Inference on relationship between gene expression and methylation can be made by using posterior distribution of (μ i 1, μ i 2, η i 1, η i 2) t conditional on data and parameter estimates, where μ i 1 and η i 1 are mean parameters of gene expression and methylation in WT and μ i 2 and η i 2 are mean parameters of gene expression and methylation in the resistant cell line.
Our technique can search topology and numerical parameters of mathematical expression simultaneously.
The parameters of such expression were optimized in order to provide a tool for the design of an industrial scale reactor using the catalysts considered.
We tested for changes in quantitative genetic parameters of HSP70 expression in a half-sib design where individuals of the beetle Tenebrio molitor were maintained in constant and varying thermal environments.
We developed a computational pipeline (BayFish) to infer the kinetic parameters of gene expression from smFISH data at multiple time points after gene induction.
More advanced methods attempt to match data-set specific parameters of the expression value distributions between input sets.
Quality control parameters of gene expression arrays are shown.
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