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Bayesian nonparametrics [34] offers a solution to this problem by including these parameters in the inference of the model.
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The choice of parameter k, used in the inference of Boolean tables to define the threshold of significance (equations (3) and (4)), obviously affects the number of links, as shown in Figure 5: with a high value of k only few links are included in the network, more are added if k decreases.
We note that Ima2 provides posterior distributions of parameters, such that the confidence in the inference of each parameter can be obtained from observing the spread of the posterior distribution.
Then the parameters were fixed and used in the inference of a Maximum Likelihood tree using a heuristic search with 20 random sequence additions with NNI swapping.
Note that the resulting plug-in approximation ignores the uncertainty from estimating the w i in the inference of demographic parameters.
The methodology enables a rigorous determination of the uncertainty in the inference of the source parameters (e.g., location, emission rate).
Despite the diagnosis of FIRS being clinical and based on serum parameters, the findings in the current study allow the inference of FIRS diagnosis in the autopsied children, based on an in situ liver analysis of these markers.
Despite the diagnosis of FIRS being clinical and based on serum parameters, the findings in the current study allow the inference of FIRS diagnosis in the autopsied infants, based on an in situ liver analysis of these markers.
We demonstrate the accuracy and efficiency of the approach on nonlinear inverse problems of varying dimension, involving the inference of parameters appearing in ordinary and partial differential equations.
The issue of SNP ascertainment bias in the design of arrays has received considerable interest, in particular for its effects on the inference of genetic parameters [ 38].
In this study, we compared our approach with a methodology for the inference of indel parameters implemented in lambda.pl, part of the Dawg package.
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