Proportions of patients with complete response, utilities, and risks of infection and other adverse events were varied randomly according to a beta distribution; costs were varied according to a log-normal distribution; and the Weibull and Gompertz parameters for progression-free survival and survival post disease progression were varied according to a normal distribution.
For the purpose of later validation of a parameter for progression of pathology, to be derived from computerised image analysis, based on the measurements acquired, sections were grouped using histopathological criteria, as follows: N: normal artery: intima only a few cells in width along full circumference.
Pre-therapeutic serum GGT is a novel and independent prognostic parameter for progression-free survival of patients with endometrial cancer.
Generally, clinical and pathological parameters such as tumor grade, tumor stage, lymphatic invasion, tumor size, CIS, papillary or solid tumor architecture, and multifocality have been considered useful prognostic parameters for disease progression in NMIBC.
Therefore, several conservative assumptions had to be made with regards to parameters for disease progression or CC mortality rate.
Absolute CD4 T cell counts and haemoglobin level are the most important parameters for monitoring progression of HIV to AIDS and also the improvement after initiation of antiretroviral therapy (ARV).
Multivariate Cox regression analysis was used to demonstrate the potential clinical value of AQP3 expression and other clinicopathological parameters for recurrence, progression and cancer-specific survival.
The parameters for CIN progression and regression (but not for HPV infection rates) were based on a review of the literature [ 12] and were then more precisely estimated, as previously described, using data from a well-characterised screened population (Australia) after accounting for detailed screening behaviour and screening test accuracy [ 12].
In the present study we explored the prognostic significance of several volumetric parameters for the progression-free and the overall survival in glioblastoma patients.
