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Training was firstly done in NeuroModelerPlus [20] using DC and bias-dependent S parameter data for 400 iterations.
B. TMDL Implementation "As a water quality manager, I need to be able to download parameter data for use in running TMDL models.
The availability of clinical parameter data for each sample was highly variable; therefore, we focused on those parameters that had the most complete annotation among the largest number of samples.
The pharmacokinetic analysis included all patients who received motesanib and erlotinib with or without gemcitabine and who had evaluable plasma samples; the GLSM analysis included only patients with available pharmacokinetic parameter data for the protocol-specified treatment.
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For pharmacokinetic parameters, data for plasma drug concentration following administration of each drug, plasma elimination half-life, plasma unbound protein fraction, and the presence of active metabolite were collected from clinical trial results.
In case of these dental parameters data for Berlin were adjusted to full mouth to allow comparisons with the other centers.
Once data were transformed into velocity- and weight-independent parameters, data for each rat were averaged such that the average gait profile for an animal directly corresponded to a single histological profile in the correlation analyses described below.
Fastq files derived from per-sequencing-lane bamfiles were re-aligned to the reference sequence using the Novoalign program (http://www.novocraft.com) with default parameters; data for this stage were grouped by technical replicate samples.
For example, a model cited by the NRC committee for how Escherichia coli protect against heat shock (El-Samad et al. 2005) consists of a set of 31 differential-algebraic equations with 27 kinetic parameters, data for many of which are not yet available.
For each parameter, data are presented as average ± SEM.
For each parameter, data will be compared between the exposed and non-exposed groups.
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