Sentence examples for paralleled by a marked decrease from inspiring English sources

The reduction in Angptl4 mRNA was paralleled by a marked decrease in ANGPTL4 protein, particularly the glycosylated form of ANGPTL4.

The decrease of cell viability after exposure to TRAIL was paralleled by a marked induction of apoptosis, as became evident from light microscopical evaluation of HE-stained cells, which had been shown to be a highly sensitive and specific method for the assessment of apoptosis (Gerharz et al, 1999; Ramp et al, 2000, 2001).

As shown in Figure 5A, we found a significant decrease in the levels of the anti-apoptotic Bcl-2 or Bcl-XL proteins paralleled by a marked increase in the levels of the pro-apoptotic Bax protein in irradiated cells compared with controls.

This was paralleled by a marked downregulation of cyclins E and A upon SMIP004 treatment.

This was paralleled by a marked increase in SFKs phosphorylation (P <0.001).

The robust induction of apoptosis observed in hypoxia was paralleled by a marked caspase 8 activation.

This latter phenotype was paralleled by a marked increased expression of genes involved in fatty acid and cholesterol synthesis.

When compared with placebo, dupilumab induced a significant decrease in asthma exacerbation rate during withdrawal of inhaled therapy with corticosteroids and long-acting β2-adrenergic agonists, paralleled by a marked improvement of respiratory function and by reduced levels of Th2-associated biomarkers such as eosinophils, exhaled NO, and eotaxin-3 [ 76].

This was paralleled by a marked upregulatory response (>6 fold) in the expression of COX-2, reproducing the same response found in vivo, whereas the exposure to malonate downregulated the expression of MAGL and FAAH.

mTOR inhibition by rapamycin was indicated by a marked decrease in p-RPS6 and paralleled by a significant reduction of phospho-Ser129 h α-syn.

The 25 30 % reduction in amyloid plaque load and Aβ plaque numbers in the B and T cell-deficient PSAPP/Rag2 ko mice was accompanied by a marked decrease in soluble and insoluble brain Aβ40 and Aβ42 levels and paralleled by a mild increase in plasma Aβ42 in comparison to the PSAPP mice (Fig.  1a c).