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In parallel, targets such as Cdh1, Cer1 and Eomes are upregulated in Bra−/− mouse embryos (supplementary material Table S5).
To clarify the contradictory roles of osteo-promoting SMAD1 and osteo-inhibitory CDK6 and TOB1 as parallel targets of miR-26a and miR-26b, we directly analyzed target protein abundance by quantitative Western blotting (i) during osteogenic differentiation of USSC and (ii) in response to transfection of USSC with miRNA mimics.
Even though we did not focus our investigation on the effect of UCN-01 on PDK1 kinase activity, it is conceivable that via inhibition of PDK1, which occupies an apical position in regulating multiple downstream kinases, UCN-01 can simultaneously inhibit multiple parallel targets including PKC, MEK/ERK1/2 and Akt.
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Then, the source exemplars are replaced with related parallel target exemplars extracted from clean audio features.
The new parallel target dictionary is given by (hat {mathbf {A}}^{t} = mathbf {W} mathbf {A}^{s}).
Finally, in Experiment 3, we designed stimuli to preclude parallel target processing to examine resilience within a serial model.
Any point (outside the regular polygon) residing between a pair of parallel target lines is dominated by only a line segment parallel to these two lines.
In addition, for MaF9 with an even number of objectives ((M = 2k) where (k ge 2)), there exist k pairs of parallel target lines.
In the dictionary adaptation stage, speaker adaptation is conducted in order to obtain a target dictionary from a source dictionary using a small amount of (parallel) target speech data.
Such association and track refinement steps will take place after every TSSG update, using the output of the TSSG tracker to form the position-measurements (29) for the ensuing parallel target trackers, one for each target.
Meanwhile, the online marketplace will be developed in parallel, targeting a higher tier market than other stock photo sites like Shutterstock or Getty, with pricing ranging from around $250 to $500 per photo – a market segment which Gutsol notes has no clear leader at this time.
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