Exact(4)
The observed 13C13C and 13C31P distances are consistent with a tightly packed architecture containing only parallel stems in a repeating structural motif within the peptidoglycan.
Binding of an 19F-labeled eremomycin analog in the FemA cell wall matches that of binding to the parent-strain cell wall and reveals the proximity of parallel stems in the alternating parallel perpendicular mixed-geometry model for the FemA peptidoglycan lattice.
When RNA can chose between a single straight stem and a group of stems that fold back on themselves, there is a good chance that the latter will be selected because of the increased interaction between neighbouring (parallel) stems.
This sort of lattice is unlikely for FemA because the short bridge would result in parallel stems that were only 5 Å apart, less than half the separation of stems in wild-type S. aureus.
Similar(56)
The actual structure has highly organized coaxial and parallel stem stacking [23].
To obtain the whole structure, more consideration for very complex coaxial stacking arrangements and parallel stem construction will be needed to stabilize the known structure.
The extensive coaxial stacking and parallel stem stacking interactions are likely to contribute at least this much to the free energy of the structure.
The structural mapping design of vsfold5 permits development of advanced coaxial stacking and parallel stem arrangement in the form of modules and methods.
The P1 and P3 stems are easily obtained with vsfold5, but P2 and P7 (the neck of the structure) appear quite difficult to obtain without introducing corrections that address these complex coaxial stacking and parallel stem configurations as well as permitting a variable Kuhn length in the design of the program.
Self-renewing, parallel stem cell division produces two daughter stem cells, whereas perpendicular stem cell division yields one differentiating daughter cell and one stem cell ([ Siller and Doe, 2009] Figure 8E).
An all-parallel-stem lattice is impossible for FemA because the monoglycyl bridge is too short (see above).
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