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Although these methods can achieve parallel, sensitive detection of SNPs, they are complex, multistep techniques that require costly modified primers and are often plagued by issues related to enzymatic efficiency and product separation.
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Sensitivity to siRNA-mediated MYC knockdown did not parallel sensitivity to the CDK4/6 inhibitor PD0332991; instead MYC-independent cell lines were generally sensitive to PD0332991.
For example, hundreds of proteins can be identified in parallel with sensitive mass spectrometers for detection and analysis of individual peptides in complex protein mixtures.
However, the paradigmatic sensory device for animals with nervous systems is a multicellular spatially extended sensor array consisting of many parallel operating sensitive cells, with the retinal and skin surfaces as prominent examples (Gibson 1966).
This provides support for the notion that emotional valence of a stimulus, perhaps via a fast parallel system sensitive to such information, serves to modulate the process of the N170.
The concept is used to describe the aqueous distribution of several pure fluids engaged in mixing sensitive parallel reactions.
However, we also need parallel strategies for sensitive community outreach and for developing strong and relevant protocols for FGM prevention.
CloudBurst is a new highly sensitive parallel seed-and-extend read-mapping algorithm optimized for mapping single-end next generation sequence data to reference genomes.
These findings are more consistent with accounts that propose that the face-specific N170 is modulated by a rapid, parallel encoding system sensitive to emotional expressions of faces [ 8].
To determine benomyl-sensitivity, cells were examined in parallel with benomyl-sensitive (tub1-1) and resistant tub2-1044) strains [ 68, 69] on 10 μg/ml benomyl or DMSO plates incubated for 2 3 days at 30°C.
We propose a model in which NADPH oxidase-derived ROIs play a central role in limiting microbial ligand-induced inflammation by interacting in parallel with redox-sensitive targets that regulate NF-κB and Nrf2 activation.
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