A similar lack of prediction between Ki67 changes and clinical response to anastrozole has been observed in the recently reported IMPACT neoadjuvant trial (Dowsett et al, 2005a) (although the short-term changes in proliferation did parallel recurrence-free survival between the three treatment groups, anastrozole, tamoxifen and Arimidex combined with tamoxifen) (Dowsett et al, 2005b).
scholar based at Stanford, has noted the unsettling parallels (the recurrence of words like "vermin," "rats" and "extermination") between contemporary anti-gold-farmer rhetoric and 19th-century U.S. literature on immigrant Chinese laundry workers.
It's not just time to recurrence.
"We're impressed by our clients recurrence rate," Azoulay said.
Thirty-one (15%) developed recurrence.
This study appears to provide reassurance that a parallel benefit in reducing the risk for local recurrence is seen, but that the recurrence score does not identify a group with a risk for recurrence sufficiently high to warrant mastectomy.
In parallel to gene expression profiling, we also analysed differentially expressed proteins in patients, from Data set 1, showing early (<6 months) and prolonged (>24 months) time to recurrence.
These results parallel the 72.2% recurrence of hallux valgus deformity.
Epigenetic deregulation of NOTCH4 signalling in OSCC was also observed, as part of a possible methylation signature for recurrence, with parallels to recently discovered NOTCH mutations in HNSCC.
Following an initial divergence, the locoregional survival curve runs approximately parallel to the time to metastatic recurrence curve, reflecting the impact of metastatic recurrence on survival in patients with locoregional recurrence.
An ideal plot corresponds to a 45° line, in which the predicted probability parallels the observed rate of recurrence and cancer-specific mortality.
