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Raskind, M. A. et al. A parallel group placebo controlled study of prazosin for trauma nightmares and sleep disturbance in combat veterans with post-traumatic stress disorder.
However despite being described as a parallel group, placebo controlled RCT, its design was complex.
One large multi-centre RCT [50] examined the efficacy of pregabalin, titrated over 2 weeks to a maximum tolerated dose up to 1200mg/day, in a multicentre, 14 week parallel group, placebo controlled RCT.
Prospective, randomised, double blind, parallel group, placebo controlled 3 year trial.
This was a 6 week, parallel group, placebo controlled trial undertaken in Roozbeh Psychiatric Hospital, Tehran, Iran during January 2002 October 2003.
The ACTION trial is a phase II randomised, double blind, investigator led, parallel group placebo controlled trial to examine the neuroprotective efficacy of amiloride treatment following ON (figure 1).
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This is a 20-week randomized, double-blind, parallel group, placebo-controlled, multicentre trial, with a 4-weeks follow up after study treatment discontinuation.
Participants will undertake a 20-week, adjunctive, randomized, double-blinded, parallel group placebo-controlled trial comparing 3 grams of adjunctive NAC daily with placebo.
In a 12-week double-blind, parallel group, placebo-controlled study, we tested the efficacy and safety of onabotulinum toxin A as prophylactic treatment for MOH.
In the current study, we will investigate the clinical effect of 3 g/day of adjunctive NAC treatment on symptoms of bipolar depression utilizing a randomized, double-blinded, parallel group, placebo-controlled design.
This study is a double-blind, randomized, parallel group, placebo-controlled trial.
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