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Of course Darwin did not consider this problem insurmountable, and spent the subsequent paragraphs addressing it as well as he could with the knowledge available to him.
In the paragraphs addressing detailed knowledge about proteasome dynamics we cite the original work.
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Other paragraphs addressed Jewish and Christian concerns with the authority of the Bible, with the land of Israel, with the moral principles of Torah and with justice and peace.
The following paragraphs address reports on meningitis caused by S. pneumoniae in Egypt.
The following paragraphs address ion channels and receptors that were and are a major focus of pain research and some of them are the focus of drug development.
In a lonely paragraph addressing the rest of the world, he shrugs off the Chinese, Vietnamese, and Cambodians, arguing that none of them "appear to have expressed their experiences of Communism this way" — presumably they did so by means other than joke telling.
We have now added a paragraph addressing the reviewers' comments.
Author response: We have added an extensive paragraph addressing this issue (which was also raised by Dr. Wingreen).
Authors may need an initial paragraph or two to persuade the reader of the validity of the methods and should have one paragraph addressing each explicitly raised question or hypothesis; finally, an additional paragraph or two might be useful to report new and unexpected findings.
A paragraph addressing these issues has been added: "By imaging completely unmodified cells, utilising recent advances in cryo-EM and acquiring tomograms of cells parallel to the tilt axis we conclude that the FtsZ ring is most likely continuous, made of shorter overlapping filaments.
A typical paragraph addressed sleeping conditions: "My wife and I sleep in a double bed.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com