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One paradoxical attribute of the SUDV mAbs 16F6, E10, and F4 and the EBOV mAb KZ52 is that, whereas KZ52 binds with a low nanomolar dissociation constant, it leaves ∼10% of virus unneutralized at high antibody concentrations (>130 nM) in both pseudotype and authentic viral entry assays.
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The first paradoxical self-reference was probably the Liar paradox, attributed to Eubulides (4th century B.C). in the form: "I am lying".
This paradoxical response has been attributed to an elevated immune response to the release of tubercular antigens; antibiotics may trigger the release of these antigens as the mycobacteria are lysed [2].
Several studies have attributed these paradoxical effects to the anti-proliferative activity of Bcl-2.
A pulmonary endothelial source of FVIII would be of particular importance to these patients whose ischaemic strokes are attributed to paradoxical thromboemboli through pulmonary AVMs [16], and who are also at risk of several pulmonary forms of pulmonary hypertension [17].
The clinical observation is that the incidence of SCC increases in patients treated with vemurafenib, which has been attributed to paradoxical increased RAF signaling due to the unrestrained activity of CRAF.
This result seems paradoxical but can be attributed to the fact that in one patient in the AUC-4 group, carboplatin was discontinued after four cycles but the patient continued to be stable on single-agent everolimus for 14 more cycles.
Although this dependence is linear, it can be attributed to paradoxical effects because at traffic intensity <1500 vehicles/h a decrease in the studied parameter in comparison with the control was revealed, and at high traffic (>1500 vehicles/h) fluctuating asymmetry index did not differ from the control (P >.05).
Second, innovation paradoxes require paradoxical management approaches.
This paradoxical result can be largely attributed to the underlying geographic shifts of urban and maritime dominance across the world, in an age of rapid globalization.
Some explanations have attributed it to the paradoxical idea that the Moon at the horizon seems larger because the brain perceives it as being farther away than the Moon at the sky's zenith.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com