His thought is clearly located within a Neoplatonic paradigm of understanding philosophy as espoused by Pierre Hadot and others.
The paradigm of understanding biological networks caricatured in Fig. 3A, with evolution as a downstream appendix, is clearly inadequate.
The advent of high-throughput technologies, together with the completion of human genome sequencing project has created a new paradigm of understanding biology by simultaneous measurement of tens of thousands of genes in each biological sample.
This was a revolution in our approach to therapeutics, representing a new paradigm of understanding immune mechanisms in animal models, using these animal models as a translational path to provide evidence to move into man and finally conducting early proof of concept studies [ 18, 20- 24].
25 As we turn our attention to new practices and paradigms for understanding the complexities of diagnosis, we cannot overlook the diagnostic tools that physicians already rely on in everyday practice.
Or so Lucinda concedes, more than twenty years after the event, embarrassed, awkward, in the company of her boyfriend, Richard Price, who has been, on every occasion I've seen them together, a paradigm of understanding, but who is unnerved by the Stanford story.
These data describe, at an unprecedented level of detail, how E2 induces organ growth and maturation and provide a paradigm for understanding the mechanisms of action of other nuclear receptors.
The insights provided by these data, into how an ER ligand coordinates transcriptional regulatory networks that result in proliferation and differentiation in a complex organ, provide a paradigm for understanding the modes of action of other nuclear receptors.
This follows the wider recognition of a 'new paradigm' for understanding dryland pastoral systems drawing heavily upon concepts of ecosystem instability or 'disequilibrium ecological theory' (Behnke et al. 1993).
