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So far, this form of hypothesis testing in humans in vivo through pharmacology generally has supported the paradigms generated in vitro and in animal models, raising hopes that a spectrum of novel therapies soon may become available to help those who have eosinophil-associated diseases.
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Although this paradigm generated accurate predictions, it fell short of a universal predictive framework.
As a result, little is known about the range of response shapes generated in the brain by common paradigms.
Although classified as complex locomotion, this paradigm generates only subtle differences in forelimb muscle activity/wrist movements and comparable changes in M1 activity when compared to simple locomotion on a linear treadmill (Beloozerova et al., 2010; Marlinski et al., 2012).
This stimulation paradigm generates enough calcium influx through either NR2A or NR2B receptors to invoke a full LTP in the CA1 hippocampus [10].
Although the cue exposure paradigm typically generates significant increases in craving in aggregate, there is considerable variation in participants' reactions and in the absolute levels of craving that are reported [ 48, 49].
In this paradigm, eIPSPs generated a transient cessation of action potential discharge.
Media companies will pioneer lucrative new paradigms for generating and consuming content (and advertising) as individuals gain hundreds of additional hours of free time in their cars every year.
System networks that are a central paradigm in biology will help us identifying new drug targets which in turn will generate more in-depth understanding of the mechanism of diseases.
Such an approach applied to West European/Mediterranean Pliocene Pleistocene series has generated a paradigm in which abundant pollen of Artemisia (a principal constituent of steppe landscapes) is correlated with glacial episodes.
The discovery of RNAi in Caenorhabditis elegans has generated a paradigm shift in how research is performed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com