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Among them, dihydrofolate reductase (DHFR) is a paradigm system for the study of the role of protein motions in enzyme catalysis, both experimentally and theoretically, because of the well-characterized conformational changes and the measured T dependence of the KIEs.
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Modern software systems are often distributed, and object-orientation is a leading paradigm for system modeling and design.
In conclusion, we present here a paradigm for systems biology approach for integration of disparate sources of transcriptional data.
DDDM is a widely used paradigm for system development and improvement (see Berwick 1998; Mandinach 2012; Orwin et al. 2012; Taxman and Rudes 2013; Wisdom et al. 2006).
Consequently, research is critical to create the foundations that can support a new paradigm for systems engineering, one that is based on the reality of engineering systems in which deterministic prediction and control are no longer possible in many circumstances.
Networks-on-Chip (NoC) is a communication paradigm for Systems-on-Chip (SoC).
The REM-based cognitive radio approach presents a new paradigm for systems design of high-speed rail broadband mobile communications.
Network-on-chip (NoC) is a new design paradigm for system-on-chip intraconnections in the billion-transistor era.
Global, systematic analysis of gene interaction networks is a recent experimental paradigm for systems biology.
Thus, our study demonstrates a promising paradigm for systems biology-based rational microbial strain engineering.
Our results reveal regulatory mechanisms underlying suboptimal non-glucose sugar fermentation in yeast, and demonstrate a promising paradigm for systems biology-based rational microbial strain engineering.
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