This paradigm states that functional subunits of the cellular maps are encoded as modules, i.e. groups of functionally related genes.
The economic constrain paradigm states that input fixity in the short run, such as access to credit, land, labor or other critical inputs limits production flexibility and conditions technology adoption decisions (Uaiene et al. 2009).
Unlike classical economics, which equates wealth with money, this new paradigm states that wealth is maximized when the largest number of people are generating ideas in a competitive, evolutionary environment.
A relatively recent paradigm states that atherosclerosis is an inflammatory disease of the arteries that can lead to ischemia of the heart and brain, resulting in infarction.
The proteinase-antiproteinase paradigm states that net MMP proteolysis in a tissue is the sum of total active MMPs minus inhibition by TIMPs.
A widely accepted paradigm states that immature DCs induce tolerance because they support differentiation of regulatory T cells (Treg) from naïve CD4+ T cells (Yamazaki et al, 2006), while mature DCs promote immunity (Hawiger et al, 2001).
Current paradigm states, that proteins with the smallest evolutionary distance and thus, the highest identity/similarity, to the target, should achieve the highest performance.
Whether the paradigm states that the sun rotates around the earth or that, on the contrary, the earth rotates around the sun has no effect on sun and earth.
The current paradigm states that a few of the transformed cancer cells, presumably a few of the cancer progenitor cells, go through EMT to produce a metastatic form of cancer.
The generally accepted simplified paradigm states that double-stranded breaks activate ataxia telangiectasia mutated (ATM) kinase, while stalled replication forks and single stranded DNA damage activates ATM and Rad3- related (ATR) kinases [1], [2], [3], [4], [5].
