To overcome these limitations and to reduce the workload for mutant analyses, Saumweber (2007) has introduced a one-odor version of the paradigm (subsequently employed in Selcho et al. [2009] as well as the companion paper of Chen et al. [2011]); notably, the paradigm maintains the reciprocity required to draw conclusions about the associative nature of the learning process.
The interest in naturally arising regulatory T (TR) cells as a paradigm for maintaining immunological self-tolerance has undergone an explosive re-emergence in recent years.
As a staff member of the Menninger School of Psychiatry (1946 51) in Topeka, Kansas, he received training in psychoanalytically oriented clinical psychology and performed research guided by the so-called "new look" paradigm, which maintained that perception, cognition, and personality interact in complex ways.
To be able to study localization of strain, the doublescale approach is coupled with a local second gradient paradigm to maintain mesh objectivity when shear bands develop.
These findings question the generality of the small-population paradigm that maintains substantial genetic variation is necessary for short- and long-term persistence.
Thereafter, the saccharin solution was limited to the first three hours of the dark period and this limited access paradigm was maintained for three weeks prior to GHS-R1A antagonist treatment.
This classic paradigm was maintained until 2005, when a distinct lineage of proinflammatory Th17 cells was identified [ 23, 24].
The Th1/Th2 paradigm was maintained until some years ago when a third subset of CD4+ effector Th cells, named Th type 17 (Th17) cells, was identified [ 39, 40].
This classical paradigm was maintained until 2005, when a distinct lineage of proinflammatory Th cell subsets, termed Th17 cells, was identified [ 16, 17].
Despite the heterogeneity of CD4+ effector Th cells being higher than previously thought and some of their subsets exhibiting high plasticity, the Th1/Th2 paradigm still maintains a strong validity.
