To mimic the presence of hydrophobic contaminants on paper for this study, filter paper strips have first been impregnated with linseed oil.
Eligible papers for this reproducibility study were studies on diagnostic accuracy published in 2000 in one of the following 12 journals: Annals of Internal Medicine, Archives of Internal Medicine, Archives of Neurology, BMJ, Circulation, Clinical Chemistry, Gut, JAMA, Lancet, New England Journal of Medicine, Neurology, Radiology.
Of a total of 1195 papers available for this study, 151 did not have adequate nation of origin assignments available within the metadata.
The research team selected the digital databases to acquire papers for the study.
We would recommend any of the methodologies listed in this paper for the study of changes in miRNA expression.
Further calculations show that only 130 unpublished research papers are needed for this study to nullify the mean of 0.6 below 0.05 level.
Whenever sufficient, we also considered information obtained from abstract in the English language with the main text edited in other languages; a total of 156 papers were selected for this study.
(That's not exactly the language they used in their paper, but...) For this study, scientists from the University of Portsmouth and the Federal University of Santa Maria in Brazil exposed zebrafish (so, again, decidedly not actual humans) to taurine an amino acid that's in a lot of energy drinks—alcohol, and a combination of the two, and then studied their behavior.
Finally, as mentioned in the results section of this paper, the data for this study were collected in 2009.
*Primary paper for the study or the most recent analysis of the cohort.
