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According to these results, we strongly recommend the use of a panel of reference genes instead of only one.
Our goal was to design and evaluate a genome-wide panel of reference genes from different functional classes.
Further binding assays using a panel of reference glycosphingolipids showed a specific interaction between the F6 fimbriae and a number of neolacto core chain (Galβ4GlcNAc) glycosphingolipids.
The method was validated using a panel of reference DNA from the University of California, Los Angeles, International DNA Exchange Program.
Minimum inhibitory concentrations (MICs) were determined against a panel of reference strains and clinical isolates of bacteria associated with infection in humans and correlated with the DNA gyrase inhibitory activity.
To evaluate performance of the new chip-based system, median lethal concentrations (LC50) of a panel of reference toxicants obtained on this system were compared with those from tests using conventional static protocols, and were not significantly different.
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In order to capture reads containing partial intron sequences, a comprehensive panel of references was designed by appending 50 bp of intron sequences extracted from the IMGT/HLA database to sequences from both ends of a reference exon.
Our method can also use existing panels of reference haplotypes.
These two reasons explain why, in practice, it is not difficult to recruit members for panels of reference.
Model organisms like human and cattle benefit from high-quality reference genomes and panels of reference genotypes that aid in imputation accuracy.
In nonmodel organisms, however, genetic and physical maps often are either of poor quality or are completely absent, and there are no panels of reference genotypes available.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com