Sentence examples for panel of mutations from inspiring English sources
A panel of mutations was introduced into residues substantially displaced upon the G93A mutation.
The panel of mutations and variants was tested against 386 blinded samples supplied by "authority" laboratories highly experienced in cystic fibrosis transmembrane regulator genotyping; >98% concordance was observed.
Commercially available CF carrier screening panels offer a limited panel of mutations, however, making them insufficiently sensitive for certain groups within an ethnically diverse population.
For example, Gordon et al.3 recently demonstrated that a curated panel of mutations and genes known to cause drug resistance in S. aureus was sufficient to predict resistance for 12 antibiotics with a sensitivity of 97% and specificity of 99%.
A preclinical positron emission tomography (PET) study was performed in mice bearing NSCLC xenografts with a representative panel of mutations: an EGFR-WT xenograft cell line (A549), an acquired treatment-resistant L858R/T790M mutant (H1975), and a treatment-sensitive exon 19 deleted mutant (HCC827).
A previous study identified a large panel of mutations that abolished PlexinB1-mediated COS7 cell collapse (Bell et al., 2011).
Pre-amplification is currently validated in our laboratory for a subset of the full panel of mutation tests, including the majority of tests for mutations in BRAF, EGFR, KRAS, NRAS and PIK3CA.
Sensitive testing can be streamlined by using a tailored and concise panel of mutation-specific tests that span the protease and RT regions, followed by sequencing the mutation-specific amplicons from positive tests to evaluate for linked mutations.
A large panel of Mutation Accumulation (MA) lines is scored for allele length at fifty-four perfect dinucleotide repeat loci.
For these, a large panel of mutation positive and other sequence variant controls were used to test the ability of the amplicons to identify sequence variants.
We summarize the use of commercially available panels of mutations – such as OncoCarta™ or other combinations – and their concordance with results obtained by using other technologies, such as next generation sequencing.
