These findings suggest the recruitment of alternative reward pathways associated with palatable drinks compared to those of cocaine.
This enduring effect was specific for palatable drinks in that both the intake and motivation for cocaine were not affected by sugar overconsumption.
A reduced motivation and reward function for palatable drinks or foods following sugar overconsumption might have a positive impact on health in certain disorders, such as bulimia, overeating or binge eating, which all present a component of increased hedonic eating [43], [44].
However, patients were offered the same nutritional formulation for MEN as they were given for EEN which raises questions as to whether an alternative, potentially more palatable nutritional drinks for the individual patients could be used for maintenance.
Previous reports have indicated that administration of the central cannabinoid receptor (CB1) antagonist SR141716A decreases intake of highly palatable food and drink.
Specifically, these mice have heightened fearfulness/anxiety-like behavior [ 41], anhedonia-like behavior, as assessed by decreased consumption of palatable food and drink [ 41, 42] and decreased sensitivity to rewards [ 43], and physiological symptoms (decreased weight gain and grooming behavior (e.g., [ 44]).
I carry a parosmia first aid kit: cinnamon drops to make drinks palatable; hot sauce to mask the taste of food.
If it has an alcohol content of over zero percent, and is at least semi-palatable, I'll drink it.
The lack of association with non-core items may be because children almost universally like highly palatable snacks and drinks (Wardle et al. 2001; Russell and Worsley, 2007; Wardle and Cooke, 2008).
