Sentence examples for pairs of mutations from inspiring English sources

While it has long been appreciated that topographic complexities on fitness landscapes can arise only as a consequence of epistatic interactions between mutations, evolutionary genetics has mainly focused on epistasis between pairs of mutations.

Three pairs of mutations were inserted.

In these screens, pairs of mutations are systematically combined, and the effects on viability are determined.

Moreover, these pairs of mutations were the major means of acquiring the ability to grow on pyrimidines at high temperature.

Three different pairs of mutations, including G186V and V226I, H183L and V226A, or H183L and D188Y, have been identified in egg-adaptation of Fujian virus [4], [39], [40].

The beneficial mutations identified span multiple pathways, and we identified pairs of mutations that individually provide only minor decreases in antibiotic susceptibility but that combine to provide higher tolerance.

For significant polymorphisms, FDR probabilities were calculated across pairs of mutation types: across transitions and transversions or across missense and silent changes.

Another commonly isolated suppressor from the prkaca-L173A background acquired a pair of mutations: K28N and E311V.

The third pair of mutations - V178S, H179D - target the last hydrophobic residue of the second putative 1-8-14 1-8-14 1-8-14(AA 165–178).

For example, homologous recombination events between any pair of mutations will gradually scramble any linkage between the mutation pair at a rate that is proportional to the physical distance between them, the recombination rate, and the passage of time.

For a given codon position pair, the strongest covariation value θ for any pair of mutations at the two positions (of the designated type: (A,A), (A,S), or (S,S)) was displayed in the map.