Sentence examples for pairing to its from inspiring English sources

Once incorporated into a RISC complex, the miRNA strand guides the complex by imperfect base pairing to its targets (reviewed by Kim et al [ 3]).

Several studies indicate that the RAS oncogene is a direct target of let-7, which negatively regulates RAS by pairing to its 3' UTR for translational repression, and some recent studies have focused on let-7 miRNA binding site polymorphisms in the KRAS 3' UTR that have been associated with reduced survival in oral cancers [ 51].

miRNAs are a set of noncoding RNA sequence of 19 to 25 nucleotides that play a major role in regulating gene expression by degrading its target coding mRNA and by repressing protein translation through partial or complete base pairing to its complimentary sites on target mRNA [ 31]. miR-125b and miR-504 were described as bona fide negative regulators of p53 in human cell lines [ 32, 33].

"Undertow" is the most archetypal Warpaint song in that its lyrics, sung in tandem by Ms. Kokal and Ms. Wayman, are perfectly paired to its tone, both aquatic: Your brown eyes are my blue skies.

The new device will also allow consumers to opt into a new "youth prevention feature set" which will keep the device paired to its owner.

In other cases, four sets of distribution parameters and a threshold value are required to create a composite distribution, one pair applying to the left of the threshold (where the true and false negatives are found) and the other pair to its right (where true and false positives are found).

The Hopf map S3 → S2 sends any such pair to its ratio.

The guide strand tends to be the one whose 5' end is less stably paired to its complement, but strand selection is unaffected by the direction in which dicer cleaves the dsRNA before RISC incorporation.

Slide as a measure of flexibility is the relative displacement of one base-pair to its neighbour along the direction of the long axis in a dinucleotide step.

Each sample was also paired to its corresponding control.

When base paired to its target sequence the miRNA down regulates gene expression of the target transcript.