Sentence examples for paired linkage from inspiring English sources

For all genes represented in our data by two or more SNPs, we computed paired linkage disequilibrium (LD) using the Haploview software and carried out haplotype analysis using the haplo.stats R-package.

A total of 212 markers were assigned to the paired linkage groups in the map.

Merging the paired linkage groups into one resulted in a distance larger than 50 cM between the two groups of markers.

To begin, we systematically classify the major sources of discretion in sib pair linkage analysis.

Bouchard C. Genetic epidemiology association and sib-pair linkage: results from the Quebec Family Study In Bray GA, Ryan DH (eds) Molecular and Genetic Aspects of Obesity.

Sib-pair linkage statistics and Haseman-Elston regression identified 19 linkage peaks, with interesting results for chromosomes 1p31.1, 15q14-q22, 17p13.3, and 21.

Sib pair linkage analysis of a dichotomous trait is a popular method for narrowing the search for genes that influence complex diseases.

Finally, we describe a new, freely available computer program, Splat (Sib Pair Linkage Analysis Testing), that can perform any sib pair statistical test currently in use, as well as any user-defined test yet to be proposed.

In this study, we investigate the impact that the degree of LD, marker allele frequency, and association type have on estimating the probabilities of sharing alleles identical by descent in multipoint calculations and hence on type I error rates of different sib-pair linkage approaches that assume LE.

Interpreting analyses of continuous covariates in affected sibling pair linkage studies.

Importance sampling method of correction for multiple testing in affected sib-pair linkage analysis.. BMC genetics.