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In contrast, the two adrenal tissues and both fats were the closest pair of tissues.
Significance values were generated in nonparametric tests separately for each pair of tissues.
PSRs that are absent in one of the pair of tissues will be filtered out.
A replicate hybridization with dye-reversal was performed for each pair of tissues.
For each pair of tissues, we plot the array probes with between-tissue correlation >0.75.
Genes that were expressed differentially between any pair of tissues were selected by cuffdiff, a tool package within Cufflinks.
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Genes which were significantly different in any pair of tissue types were kept for further analysis.
A pair of tissue samples for each case was collected from the tumor tissues and their corresponding noncancerous colon tissues.
First, for each pair of tissue comparison, we use the estimation of overall gene expression to normalize the expression signals of each exon.
The abstraction involves a pair of tissue specific dynamical system models of the same biological process, both manipulated synchronously through a set of common input functions.
We computed the Pearson correlation across genes for each pair of tissue biological replicates and eliminated from further analysis any tissue for which this correlation was less than 0.98 for any biological replicate pair (Additional file 3: Table S6).
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CEO of Professional Science Editing for Scientists @ prosciediting.com