Sentence examples for pair of substitutions from inspiring English sources

Two of these are conservative changes (Val87Ile and Leu361Ile) while two others entail substitution of an alanine for another small residue (Ala326Cys and Ala342Ser); the remaining pair of substitutions (Pro161Ala, Ala189Pro), while not so obviously conservative, can readily be accommodated within the protein core as judged from their excellent packing scores.

A pair of substitutions, which does not impact the GC content but has been found to be positively correlated with recombination rates is G C→C G [ 12].

RNAs having substitutions with a bias towards codon usage are likely to code for polypeptides whereas pairs of substitutions that maintain stem-loop structures have a higher probability to reflect secondary structure conservation of non-coding RNAs.

If one or more pairs of substitutions improved the model (ie reduced the mean loss) we fixed the pair that produced models with lowest mean loss and then repeated the process.

Since computational resources are cheap we instead used the 1000 subsamples of the training sets to "virtually" test which pairs of substitutions led to better predictions by our algorithms.

B provides an unbiased sample estimate of the effective number of acceptable amino acids at a site, because it can be interpreted as the fraction of pairs of substitutions of the ancestral amino acid where the new amino acids are different from each other.

Although there are other methods for identifying descendant copies from multiple master sequences (i.e., splitting subfamilies based on shared pairs of substitutions) (Price et al. 2004), the method we chose can be applied to both fully sequenced genomes and low-coverage shotgun data, enabling comparisons between salamanders and other vertebrates.

The generalized continuous-time Markov process coevolutionary algorithm (GCTMPCA) [ 3, 6] employs maximum likelihood to determine if pairs of substitution events are more likely under a dependent or independent model of evolution.

Or perhaps Coach Silvia Neid made a tactical mistake, using a pair of defensive substitutions while leaving the attack-minded winger Fatmire Bajramaj and forward Birgit Prinz, the Women's World Cup's career-leading scorer with 14 goals, on the bench.

In an attempt to stem the tide, a pair of emergency substitutions were made - Adam Jones and Matthew Rees were brought on to join Gethin Jenkins in the front row.

For the mouse rat pair, only 8 10% of substitutions were accumulated because they diverged ∼12 to 24 Ma (Rat Genome Sequencing Project Consortium 2004).