Comparison of S with general classes of resolution-based quality criteria functions (Rs, Rp, and Rmin) shows superior features such as correct assessment of favorable separation conditions, preservation of peak pair contributions, elimination of arbitrary cut-off values, and a unique capability to interpret absolute significance of function values through a simple inequality.
The magnitude of ion pair partitioning contributions to the log D7.4 measurements of 24 acidic drugs are investigated, and the risks to drug discovery projects that ignore such contributions are discussed.
The response is given by a sum of terms involving the interaction of a pair of global modes, the contribution of each pair depending on the appropriate elements of the distribution matrices.
However, for PPAs 5, there is a contribution from the phosphorus lone pair of the phosphole, whereas the contribution of the P=S is smaller for the oxidized PPAs 6.
If one or both variables of a pair were significantly related to the outcome, those pairs of variables were evaluated in terms of their contribution to the model r; the pair of variables that made the largest contribution to r was entered into the model.
But after a certain SFR threshold pair, the contribution of pico edge users towards the average rate eventually dominates.
Pairwise contributions that have large magnitudes could be overshadowed by the accumulation of pair-wise contributions having small magnitudes or opposite signs.
Equilibrium binding curve for ABA1; control experiments for aptamer pair binding; contribution of linker length to binding affinity for bidentate aptamer reagents; binding affinity measurement for ABA1-ABA65 using ELONA; binding affinity measurements for control sequences; table of aptamer array features; table of screened aptamers, bivalent aptamer reagent constructs and control sequences.
For each pair of regions, we calculate the contribution of (small) changes in transportation costs to specific outcomes, considering different dimensions of regional policy.
Our model is based on the "two-state" approximation (Von Hippel and Berg 1986; Gerland et al. 2002), which assumes the binding affinity is a sum of contributions of opposing amino acid nucleotide pairs, with each contribution being of only two types, "matched" or "mismatched".
